This project, as an investigation and scientific thesis, involves a number of issues regarding the influence of Christian Slavic immigrants in the Province of Misiones (Argentina Republic). Although the field work is historical, the project is also related in in the academic arena of the missiology study. In general, the project was designed as a part of the Slavic immigrant´s roles on the Provincial context, from the historical perspectives. First, Slavic immigrants played a leading role in the formation of communities and influenced the country as a multicultural society. Secondly, the Slavic community contributes its brick in building a singular and dynamic context in Argentina and different demographic areas in Latin America.